Post Cycle Therapy (PCT) is the protocol used after a steroid cycle to restart the body's natural testosterone production, preserve muscle gains, and restore hormonal balance. Skipping PCT is one of the most common — and most damaging — mistakes in steroid use.
When you introduce exogenous androgens (steroids), your hypothalamic-pituitary-gonadal (HPG) axis detects elevated testosterone levels and suppresses its own output. The longer and heavier the cycle, the more suppressed natural production becomes. Without PCT:
The timing depends on the half-life of the steroids used in your cycle:
| Steroid Type | Examples | Start PCT After Last Injection |
|---|---|---|
| Short esters | Testosterone Propionate, Tren Ace | 3 days |
| Long esters | Testosterone Enanthate, Deca | 14-18 days |
| Oral only | Dianabol, Anavar | 24-48 hours after last dose |
Clomid is a selective estrogen receptor modulator (SERM) that works at the pituitary level — it blocks estrogen feedback, causing the pituitary to release more LH and FSH, which directly stimulates testicular testosterone production. It is the most powerful PCT drug for restarting the HPG axis.
Nolvadex is also a SERM but works differently to Clomid — it is particularly effective at blocking estrogen at the breast tissue, making it the primary defence against gynecomastia. It also stimulates LH release, though slightly less potently than Clomid. Nolvadex and Clomid are often run together.
HCG mimics LH and directly stimulates the testes to produce testosterone. It is used during long cycles (to prevent testicular atrophy) or in the 2 weeks before PCT begins. HCG should not be run throughout PCT as it can suppress natural LH production.
Weeks 1-4: Nolvadex 40/40/20/20mg/day
2 weeks pre-PCT: HCG 1000IU EOD
Weeks 1-6: Clomid 100/100/50/50/25/25mg + Nolvadex 40/40/20/20/20/20mg